Applications of flow-through coulometric detector with renewable working material based on carbon spherical microparticles
2016
Abstract
This paper maps the development and testing of recently presented flow-through coulometric detector with renewable working material based on spherical carbon microparticles, all the way from its construction and testing to application on pharmaceuticals determination or samples with complex matrix such as urine. It was firstly tested on electrochemically well defined model samples: potassium ferrocyanide and hydroquinone to characterize its general electro-chemical properties.
Later, the applicability of the detector was proved by determination of tyrosine and thymol by flow injection analysis and of sulfamethizole and mixture containing homovanillic and vanillylmandelic acid by HPLC.