Bile Acids: Possibilities of Anodic Oxidation in Non-aqueous and Mixed Media at Selected Electrode Materials
Abstract
Bile acids are not considered to be highly electrochemically active nor at negative neither at positive potentials. In this study the possibilities of their electrooxidation on platinum, glassy carbon, highly oriented pyrolytic graphite and boron-doped diamond electrodes were investigated in acetonitrile and mixed media acetonitrile:water using perchloric acid as a supporting electrolyte.
The presence of bile acid in solution can be traced as earlier onset of anodic current compared to supporting electrolyte solution or as well developed voltammetric signals at reasonable potentials of around +1.2 V (vs. Ag/0,01 mol l-1 AgNO3/1 mol l-1 NaClO4) when using minimal content of water in acetonitrile.
Factors influencing the stability of this signal, especially using boron-doped diamond electrode need to be further investigated.