Utilization of Carbon Paste Electrode for the Determination of Selected Catecholamine Metabolites

Abstrakt

Methods utilizing differential pulse voltammetry and HPLC with amperometric detection were developed for the simultaneous determination of two catecholamine metabolites, homovanillic acid and vanillylmandelic acid. Low selectivity of the voltammetric method was limiting for the determination in urine samples; inclusion of chromatographic separation enabled the application even in this complex sample.

Klíčová slova

• Glassy carbon paste electrode
• Homovanillic acid
• Vanillylmandelic acid
• Amperometric detection
• Differential pulse voltammetry