Abstract
Renal cell carcinoma (RCC) is the most malignant urological tumour and the incidence of RCC in the Czech Republic is currently highest in the world. In recent years a new findings in molecular pathophysiology improve our knowledge and ability.
Kidney cancer is associated with seven different genes and is characterized nowadays as metabolic disease. Improved diagnosis and development of new treatment methods allows much greater individualization of the care.
A significant proportion of patients with RCC is still primarily diagnosed in an advanced stage of disease or progression occurs during the follow up. The basis of the care for patients with RCC is a comprehensive assessment and treatment, especially surgical or integrating or other minimally invasive ablative techniques in the treatment system.
The review summarizes current trends in therapy and care from the perspective of urologist. metastasectomy, radiofrequency ablation, targeted therapy, personalized urooncology care.