Abstract
Suicide is a serious health and social problem whose incidence varies between genders, age groups, geographical distribution and with influence of socio-political structure of society. It has been identified many risk factors and this behavior has etiological heterogeneity.
There is no effective algorithm to predict suicidal activity in clinical practice, but increase the detection is associated with introducing the professional community and especially primary care physicians with clinical, psychological, sociological and biological factors whose can bring increasing of the recognition of vulnerable individuals and allow initiation of therapeutic interventions psychotherapy, psychopharmacology, neuromodulatory modalities or their combinations to achieve effective level of suicide prevention.