Integra(R) was first used in the Czech Republic in 2002 at the Prague Burns Centre, Královské Vinohrady Teaching Hospital to manage an extensive burn trauma in a child. Since then it has become an inseparable part of treatment of burn patients.6 This article presents our experience with the use of Integra(R) skin replacement in clinical practice since 2002.
We evaluated even the early patients after a long period from the first application. The obtained clinical data were correlated with the results of histological assessment of scar tissue after the application of Integra(R) and DE graft.