Abstract
Study objective: The objective was to analyse and evaluate a cohort of Lyme borreliosis (LB) patients with neuroborretosis (LNB) hospitalised in the Czech Republic in 2003-2013. Material and methods: Data analysed in this study were obtained from the National Register of Hospitalised Patients, which is a nationwide population register maintained at the Institute of Health Information and Statistics of the Czech Republic.
Data collection from all departments of bed care establishments are regularly processed every year. Registration of basic hospitalisation diagnoses is performed in accordance with the 10th revision of the International Classification of Diseases (ICD-10).
The study cohort consisted of 23,631 patients with clIn tally and laboratory confirmed LB hospitalised between 2003 and 2013. Results: Nervous system involvement. i. e.
LNB (ICD-1,0 codes 000-099) was recorded in 27.1% (6 392) of LB patients. Hospital admissions for LB exhibited a slight downward trend with year -on -year fluctuations over the study period.
In contrast, LNB showed an upward trend with slight year-on -year fluctuations (345-779 cases) (p = 0.003). Overall. 6,392 persons, 3,220 males and 3,172 females, were diagnosed with LNB over the 11 -year study oeriod.
Some oatients presented with multiple concomitant neurological symptoms. Overall, 6,392 hospitalised patients were diagnosed with 8,168 diseases of the nervous system.
The most common diagnoses were facial nerve disorders (21.1%), meningitis (18.3%), polyneuropathies 03.6%). encephalitis, myelitis. and encephalomyelitis (11.3%), and nerve root and plexus disorders (4.9%). The average age of male and female patients hospitalised with LNB was 44.4 and 44.7 years, respective lv.
It varied significantly' between the ICD-10 code groups < 0.001) from 38.0 to 63.0 years.