Abstract
Currently, more than 50 (60)% of renal cell carcinomas are detected incidentally on abdominal ultrasound or computed tomography / magnetic resonance imaging. These tumours are usually smaller and lower stage.Many patients with renal masses remain aymptomatic until the late stages of the disease.
RCC can become very large without any symptoms, due to the retroperitoneal position of the kidney. It has been reported that the prevalence of the classic triad of flank pain, gross hematuria and a palpable abdominal mass in some parts of the world is lower than previously observed a correlates with advanced disease and subtypes associated with poor prognosis.
Paraneoplastic syndromes are found in approximately 20 - 30 % of patients with symptomatic RCCs. A few patients present with symptoms caused by metastatic RCC.
Diagnostic tool as a history, physical examinoation and laboratory have limited information, mostly in advanced RCC only.