The first TAVI in the Czech Republic was performed in 2008 and since then, more than 90% of TAVI procedures have been involved in the online all comers Czech TAVI Registry. 1532 TAVI procedures from 2008 till June 2016 in a high risk population with symptomatic severe aortic stenosis (logistic EuroSCORE 18.2, median age 80 years) were relatively safe (in-hospital mortality 3.9%, severe paravalvular aortic regurgitation after TAVI 1.0%) and highly effective (index of aortic valve area before versus after TAVI was 0.4 cm(2)/m(2) versus 1.0 cm(2)/m(2), respectively). Majority of patients (83.7%) underwent TAVI because of their high risk for surgery assessed by the Heart team discussion and 71.9% of them were discharged home.