Neuropathogenic bird schistosome Trichobilharzia regenti activates astrocytes and microglia of infected ducks and mice
Abstract
Parasitic worms may cause serious and world-wide distributed neuroinfections, such as neu-rocysticercosis or neurotoxocarosis. However,immune processes in the affected nervous tis-sue (including characterization of the role ofglial cells) usually remain overlooked.We explored the res-ponse of avian and mu-rine astrocytes and mi-croglia to Trichobilharziaregenti, a neuropathoge-nic schistosome migra-ting in the central ner-vous system of vertebra-tes.1,2,3 .