Publication at Faculty of Medicine in Hradec Králové |
2017
Abstract
Cardiotoxicity represents a very serious adverse effect of anti-tumour therapy. Cardiotoxicity includes a broad spectrum of symptoms: myocardial dysfunction and heart failure, coronary artery disease, valvular disease, arrhythmias (especially those induced by QT-prolonging drugs), arterial hypertension, thrombo-embolic disease, peripheral vascular disease and stroke, pulmonary hypertension and pericardial complications.
The paper discusses the basic terms, mechanisms and diagnostic procedures for the detection of cardiotoxicity (ECG, echocardiography, CMR, biomarkers).