Use of electroconvulsive therapy in the treatment of organic catatonia in patient suffering from Niemann-Pick disease type C
2017
Abstract
Niemann-Pick disease is hereditary, genetically conditioned disease affecting the metabolism of sphingolipids and belongs among lysosomal storage diseases. Its incidence in general population is one in 150,000, more in certain communities, and its type C is the most widespread form.
Symptoms include a whole range of of pathologies, which may not be entirely specific, nevertheless its psychic symptoms may mimic not only psychosis, but also depression, progressive dementia and even catatonic states. Currently there is no causal therapy, enzymatic therapy is currently an approved therapeutic approach and the whole therapeutic process is focused primarily on overcoming single complications at the time.