Thrombophilia Work-up in Females with Venous Thromboembolism in Association with Oral Contraceptive Use: Results, Strategy and Clinical Application of Testing
2017
Abstract
Oral contraceptive use is one of the most common causes of venous thromboembolism in females in a reproductive age. The usefulness of thrombophilia work-up in this scenario has been discussed in the last years especially in the term of financial cost and clinical implication.
In the case of testing, it is necessary to keep appropriate timing and conditions for every assay. Methods: We analyzed thrombophilia work-up in a large cohort of 700 females with venous thrombosis in association with combined contraceptive pills use.
We focused on laboratory thrombophilia work-up in the term of an appropriate strategy of testing, the influence of oral contraceptives use, presence of acute thrombosis and type of anticoagulation therapy.