Publication at Faculty of Medicine in Hradec Králové |
2017
Abstract
Psoriasis is a chronic relapsing infammatory disease afecting 2-3% of European population. Patients with psoriasis are more likely to be smokers and have higher risk of developing metabolic syndrome (MetS).
The aim of this study was to compare infammatory markers - C-reactive protein (CRP), leptin, adiponectin, resistin and lipoprotein associated phospholipase A2 (LpPLA2) as well as the factors of MetS between patients with psoriasis (PP) and the control group (CG) witht respect to positivity of MetS and smoking history. Comparing the results of the monitored parameters we confirmed that psoriasis is an infammatory state related to obesity regardless of smoking history, but the severity of psoriasis is aggravated by smoking.