Breast conservative surgery after neoadjuvant oncologic treatment for breast carcinoma at the 1st Department of Surgery, 1st Faculty of Medicine of Charles University and General Teaching Hospital in Prague over a ten-year period (2004-2013)
Abstract
Introduction: Since the first breast conservative surgery following neoadjuvant oncotherapy performed in the 1990s, there has been a shift in indications, diagnostic, surgical and oncotherapeutic procedures. The aim of the study is to present the results of the comprehensive treatment of patients with breast conservative surgery performed after neoadjuvant oncologic treatment for breast cancer at our department of surgery.
Method: A retrospective study involving 96 patients operated on at our department between 2004 and 2013. The median follow-up time is 6 years and 8 months after the diagnosis.
Results: Breast recurrence was found in 2 (2.1%) cases. No axillary recurrence occurred.
A total of 8 (8.3%) patients with generalized carcinoma of the breast died. Total remission was achieved in 81 (84.4%) patients. 76 (79.2%) patients survive in the CR.
Conclusions: The results of the studies mentioned below as well as our results have shown that BCS after neoadjuvant oncologic therapy is safe and effective in appropriately selected patients.