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Treatment of bleeding caused by liver cirrhosis-associated portal hypertension - update of Czech Society of Hepatology guidelines

Publication at First Faculty of Medicine, Faculty of Medicine in Hradec Králové |
2017

Abstract

Variceal bleeding is one of the severest life threatening complications of portal hypertension. Appropriate treatment includes initial general management, fluid replacement and hemo-substitution, antibiotic prophylaxis, vasoactive medication, and endoscopic treatments.

A transjugular intrahepatic portosystemic shunt (TIPS) is indicated in cases of failure. A dedicated esophageal metal stent or balloon tamponade is sometimes used as a "bridge" to TIPS placement or in cases of TIPS contraindications.

Non-selective β-blockers and endoscopic therapy are used in primary and secondary prophylaxis. The following paper summarises the update to the recommendation of the Czech Society of Hepatology for this treatment.