Hodgkin lymphoma (HL) is a curable cancer in 80 % up to 90 % of younger patients but prognosis in elderly patients over 60 years is considerably worse. Elderly patients represent 10-20 % of all HL cases.
Due to the worse performance status and various comorbidities in elderly patients their tolerance of chemotherapy is significantly lower when compared to younger patients. Based on the data from published literature as well as data from the Czech Registry of HL patients this article summarizes recommended treatment, possible toxicity and outcome of elderly patients with HL.
Currently new drugs alone or in combination with chemotherapy are tested in order to improve efficacy and to reduce adverse events of treatment.