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Inflammatory bowel disease as a risk factor for colorectal cancer

Publication at Faculty of Medicine in Pilsen |
2017

Abstract

Colorectal cancer (CRC) is a feared complication of inflammatory bowel disease (IBD), dominantly in ulcerative colitis. The cumulative probability of developing this malignancy in ulcerative colitis (UC) is significantly higher than in the general population, making UC the third highest risk condition for CRC (1).

Because CRC is such a concerning complication of chronic inflammatory bowel diseases, it necessary to know the most important risk factors for its development as well as strategies for reducing incidence of this malignancy. This review presents not only the risk factors that predispose IBD patients to develop CRC, but more importantly, explores the accepted strategies for reducing this serious complication. (C) Interní medicína pro praxi, 2017.