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Lead poisoning. A surprising cause of constipation, abdominal pain and anemia

Publication at Third Faculty of Medicine |
2017

Abstract

This article reports on patient that has been presented with sudden onset of constipation, abdominal pain and normocytic anemia. Gastroscopy and colonoscopy ruled out an organic disease.

In peripheral blood and bone marrow aspirate smears,coarse basophilic stippling of erythrocyte (and erythroblasts) point out a possibility of heavy metal poisoning. The level of plumbemia exceeded 8,4 times the maximal permitted value for common (non-professional) population.

A source of poisoning was indentified from a glaze on a ceramic jug, from which the patient had drank tea with lemon for three months. A lead concentration in the tea extract was 227 mg/kg.

In developed countries, lead poisoning is a rare diagnosis. As the symptoms are nonspecific, missed diagnoses could occur, especially in sporadic, non-occupational exposure.

However, a microscopic evaluation of the peripheral blood smear with finding of predominantly coarse basophilic stippling of erythrocyte may lead to suspicion of lead poisoning.