Publication at Second Faculty of Medicine |
2017
Abstract
Adverse skin reactions to vaccines are most frequently limited to the injection site. They result from non specific activation of theinflammatory system by vaccines components or a local immune complex mediated reaction.
Rare hypersensitive reactions areeither immediate immunoglobuline E mediated or delayed T cell mediated. They are caused by different type of allergens, havea different severity and diagnostic approach.
If allergy is suspected, an allergologist examination should be done in an attempt todetermine the culprit allergen. The vaccine should be administered in a setting in which anaphylaxis can be recognized and treated.