Abstract
Human papillomaviruses (HPV) are the most important causes of cervical cancer but also other carcinomas and non-malignant lessions especially of women's and men's genital area. But not only.
Prevention of HPV infection is the primary prevention of all HPV-associated lessions. Rules of safety sex are very important but HPV could be transfer also by noncoital activities.
Ten years ago clinical history of HPV vaccination has started by quadrivalent vaccine. In 2015 it was graduated by nonavalent vaccine.
All HPV vaccines are characterized by high efficacy against including types of HPV and also high safety.