Abstract
Congenital Developmental Deficiency (VFD) is a structural, functional or metabolic health disorder that occurs during prenatal development of the fetus and is present at the birth of an individual. Congenital developmental disorders of the skin affect all three areas and are of varying severity.
In developed countries, it is reported that VVV occurs in 2-3% of newborns. If all structural and genetic disorders of skin development were included in these numbers, these numbers would be much higher.
Prenatal diagnosis is now high. There are various biochemical, cytogenetic, molecular genetic or imaging examinations that can be diagnosed with VVV, but the vast majority of VVV skin can not be prenatally diagnosed unless it is targeted specifically for genetic genomics on a family of genodermatosis.