Abstract
Brain metastases are an important and frequently treated indication in modern radiosurgery. This non-invasive method offersgood local control with minimum toxicity and repeability of treatment.
The CyberKnife is a device for frameless whole-bodyradiosurgery using image guided robotic technology and linear accelerator as a photon source. In our prospective study wemeasure the volume of brain metastases on MRI with use of computer-assisted volumetry and we evaluate the predictive valueof these volumetric changes.
We track the effect of therapy according to histological type of tumor, number of brain metastases,sex and initial performance status of patients. The group of patients with CyberKnife treateted brain metastases, that is uniquein our conditions, is then statistically analyzed and results are compared to peer-reviewed articles of institutions using the sametechnology and reference data from frame-based (Gamma Knife) radiosurgery centers are matched.