Publication at Faculty of Science, Central Library of Charles University |
2018
Abstract
Doxorubicin is an anticancer drug, which is used for treatment of various cancer types. It contains a quinone structure, similarly as some other drugs belonging to the same category (e.g., daunorubicin and epirubicin).
Its monitoring can lead to optimization of individual patient dosages and increase chances for recovery of patients. A micro-volume voltammetric cell and differential pulse cathodic stripping voltammetry have been used for determination of doxorubicin hydrochloride.
A volume of used sample was 50 μL. Limit of detection was 0.39 μmol L-1.
An applicability of this method was verified on samples of drinking water and of human urine.