Publication at First Faculty of Medicine |
2018
Abstract
Pancreatic ductal adenocarcinoma is in 80-85% of the cases located in the head of the pancreas and has the worst prognosis out of all gastrointestinal tumours, while a rise in it is still expected. The average survival rates through all the stages are currently at 6-7%.
From both the diagnostic and therapeutic point of view, locally advanced pancreatic adenocarcinoma is the most difficult entity to deal with Most pancreatic carcinomas are still diagnosed in advanced stages and at the time of diagnosis, there are distant metastases present in roughly 50% of the patients. Locally advanced pancreatic adenocarcinoma represents a highly heterogeneous group of diseases, from borderline resectable to non-resectable tumours.