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Experimental promotion of liver regeneration after portal vein branch ligation

Publication at Faculty of Medicine in Pilsen |
2018

Abstract

The aim of this publication is to summarize the possibilities of influencing liver regeneration after PVE/PVL in an experiment using cytokines (TNF-α, IL-6), monoclonal antibody against TGF-ß1 (MAB TGF-ß1) and mesenchymal stem cells (MSC). Conclusion: Application of IL-6, TNF-α, MAB TGF-ß1 and MSC seems to provide suitable stimulation for achieving faster FLRV growth.

Nevertheless, many controversial questions still remain to be answered with respect to the mechanism of their respective effects.