Perioperative tumour marker levels as prognostic factors for surgical treatment of breast cancer liver metastases
Abstract
Breast cancer represents the most frequent cancer worldwide among women and i some of the most frequent causes of death in this population. Breast cancer liver metastases in most women are associated with concurrent BC dissemination to the lungs and bones and these represent the only site of metastatic BC in 12-15% women.
Surgical Treatment of BCLM is an importatnt component of multimodal therapeutic approaches. In our view, one strategy that might improve the results of surgical management of BCLM is the search for early indicators of tumour dissemination or for prognostically high-risk patients.
The tumour markers are general indicators used in monitoring and follow-up of patients. The aim of our retrospective study was to determine whether perioperative levels of clinically routinely used tumour markers influence overal survival (OS) and recurrence-free survival (RFS) of patients undergoing resection or thermoablative therapy for BCLM as part of a multimodal approach.