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How To Interpret Elevated Plasmatic Level of High-Sensitive Troponin T in Newborns and Infants?

Publication at Faculty of Medicine in Pilsen |
2018

Abstract

Research and clinical implications on novel cardiac biomarkers has intensified significantly in the past few years. Consecutively 454 healthy full termed newborns and 40 healthy infants were enrolled in the study.

Samples of cord or venous blood were drawn and tested for hscTnT concentrations with high-sensitive TnT assay (Roche Cobas e602 immunochemical analyzer). This study has confirmed the higher reference levels of hscTnT in neonates and young infants when compared with adult population.

Many extracardiac factors as hemolysis and age may affect the hscTnT level. Based on presented results, a careful clinical interpretation of hscTnT is recommended.