Our results demonstrate that lipid peroxidation plays a significant role in the machanisms of acute methanol poisoning.The acute concentrations of three measured biomarkers were elevated in comparison with the sollow-up concentrations.Neuronal membrane lipid peroxodation seems to activate leukotriene-mediated inflammation as a part of the neuroprotective mechanisms.No cases of persistent elevation were registered among the survivors 2 years after discharge.