This publication comprises a summary of the official full text version of ''The 2018 European Heart Rhythm Association Practical Guide on the use of non-vitamin K antagonist oral anticoagulants in patients with atrial fibrillation'' originally published in English in the ''European Heart Journal 2018; 39 (16): 1330-1393, doi:10.1093/eurheartj/ehy136'' by Oxford University Press under licence from the European Society of Cardiology (''ESC'').