Publication at Faculty of Medicine in Pilsen |
2018
Abstract
The authors summarize the current status of the alkylation cytostatics ifosfamide in the treatment of solid tumors and haematological malignancies (in adult and childhood). There are the most common indications in routine clinical practice presented.
The development of resistance and side effects is a major problem of the therapy. Understanding of drug toxicity and its solutions are very important to achieve maximum effect treatment and safe application.
Therefore, the attention is focused to a summary of the current knowledge about the possible toxicity of the treatment, the baseline recommendations to address the most common side effects and their prevention.