Abstract
Anorexia nervosa is a serious, often life-threatening, disease that belongs to eating disorders, a group of diseases characterized by pathological eating behavior that need to be understood and treated throughout the bio-psycho-socio-spiritual context. Despite all clinical and research efforts, treatment outcome (the combination of regimens, psychopharmacotherapy and psychotherapy) is not satisfactory, and other therapeutic options must be sought.
In recent years, the number of studies of neuromodulation in psychiatric and neurological diseases has been increasing. We can divide these methods into invasive, minimally invasive and non-invasive methods, non-invasive group including transcranial DC stimulation (tDCS), repetitive transcranial magnetic stimulation (rTMS), chronobiotherapeutic modalities, and more.
In the available studies, tDCS appears to be a safe and well-tolerated method in the treatment of mental anorexia (AN). The studies are based on the hypothesis that stimulation of the dorso-lateral prefrontal cortex (DLPFC), which is important for emotional regulation, reduces the need for dietary behavior, either by direct action on the regulation of food intake or translocation, or by influencing comorbid psychopathology.