Longitudinal association between inflammatory markers and specific symptoms of depression in a prospective birth cohort

Abstract

Low-grade inflammation is associated with depression, but studies of specific symptoms are relatively scarce. Association between inflammatory markers and specific symptoms may provide insights into potential mechanism of inflammation-related depression.

Using longitudinal data, we have tested whether childhood serum interleukin 6 (IL-6) and C-reactive protein (CRP) levels are associated with specific depressive symptoms in early adulthood.

Keywords

• Depression
• Psychological Symptoms
• Somatic symptoms
• Inflammation
• Interleukin 6
• C-reactive protein
• Cohort study
• Immunopsychiatry
• ALSPAC
• Neurovegetative Symptoms