Acute lymphoblastic leukemia (ALL) and its treatment are associated with endothelial dysfunction (ED) and increased cardiovascular risk in adulthhood. There are no data on ED in children after successful treatment of ALL.
This is the first study that combines both plethysmographic and biochemical methods to assess ED in ALL. Significantly decreased RHI with elevated plasma concentrations of biochemical markers imply a possible association with premature ED in ALL patients.