Carbon-Based Nanomaterials and Immune System: Effect of Carbon Nanotubes and Graphene Platelets on NLRP3 Activation

Abstrakt

In our study, we focus on comparison between several types of MWCNTs and GPs depending on their internalization into cells and their intracellular distribution. All these nanomaterials are assumed to cause chronic inflammation, so we focus on their ability to induce NLRP3 inflammasome as a key mediator of inflammation.

Klíčová slova

• Carbon-based nanomaterials
• immune system
• NLRP3 inflammasome
• activation