Abstract
Authors report about a case illustrating the possibility of negative influence of repeated application of a derivate of Botulutoxin A on the eyelid position in older woman. The indication for successful surgical treatment was chronic entropium of lower lid.
This was initially ineffectively treated by means of repeated intradermal injections of in this neurotoxin. Histological examination of the excised skin and subcutis samples taken during entropium plastic surgery showed unfavorable and irreversible changes including especially scarring of the eyelid and atrophy of the stripped muscles.
Always we have to consider the frequency of application, because repeatedly used derivate of this neurotoxine causes irreversible changes in cutaneous and subcutaneous tissue.