Crystalloids and colloids are ubiquitous in perioperative and intensive care medicine. However, there is still a vivid debate about which solution has the minimal negative effect on coagulation.
The following article summarizes the existing knowledge about the influence of infusion solutions on blood coagulation measured by standard coagulation tests such as PT and APTT, and also using tromboelasthography and rotational thromboelastometry. The goal was to determine which infusion solution has the least negative effect on blood coagulation in the published literature.