Application, advantages and challenges of human biomonitoring in exposure assessment as a part of human health risk assessment process including occupational settings
Abstrakt
Human biomonitoring (HBM) has a long tradition both in health care and public health with wide range of applications including occupational settings. Its advantage is the integration of all exposure routes and sources.
Since HBM information is an integrated exposure finding, it offers the opportunity to trace and mimic a realistic exposure scenario. It reduces the number of assumptions that need to be done when estimating exposure, and thus helps to reduce the uncertainties in exposure science.
In spite of some challenges, such as further harmonization in the area of HBM, necessity to derive equivalents of markers of external exposure, but also an addressing the ethical and political aspects of its application, HBM is an efficient and costeffective way to measure the level of exposure of the human body to xenobiotics.