Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open label, blinded endpoint, phase 3 trial
2019
Abstract
Systolic pressure above 185 mm Hg is a contraindication for thrombolytic treatment with alteplase in patients with acute ischemic stroke (CMP). However, it is uncertain what the target blood pressure should be in these patients.
The aim of the study was to compare the intense lowering of blood pressure compared to the decreasing pressure as recommended.