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Modern aspects of allergic rhinitis

Publication |
2019

Abstract

Allergic diseases are seen as systemic diseases with organ symptoms. Allergic rhinitis is defined as a group of nasal symptoms, arising from an underlying IgE-mediated inflammation following exposure of the nasal mucosa to allergens.

The basic feature of allergic rhinitis is a persistent eosinophilic inflammation accompanied by typical clinical manifestations. Allergic rhinitis develops on the basis of numerous environmental factors in a genetically predisposed individual.

The symptoms of rhinitis may be spontaneously reversible or resolve following treatment. The management of allergic rhinitis involves patient education, elimination of allergens, pharmacotherapy, and specific allergen immunotherapy.

Sublingual tablet dosage form of allergen immunotherapy (grass pollens, house dust mites) is a modern alternative to subcutaneous treatment. This treatment reduces the severity of allergy symptoms, lowers the risk of developing new allergic sensitizations, and prevents the development of clinical asthma in patients treated for allergic rhinitis.