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On Histologic Variability of HPV-associated Endocervical Adenocarcinomas

Publikace na Lékařská fakulta v Plzni, 1. lékařská fakulta |
2019

Tento text není v aktuálním jazyce dostupný. Zobrazuje se verze "en".Abstrakt

We read with great interest the article by Hodgson et al1 on the newly proposed classification system for endocervical adenocarcinomas (EA) - the International Endocervical Adenocarcinoma Criteria and Classification (IECC). The authors stated that observation was based on various excisional material (loop excision, cone biopsy, trachelectomy, or hysterectomy) in 63 % of cases and exclusively on biopsy material in 37 % of cases originating from a single tertiary care institution.

Adding to the seminal paper on IECC by Stolnicu et al reviewing 409 cases with complete slide sets, we would like to share our experience with 118 hysterectomy specimens with human papillomavirus (HPV) - associated EA from 7 European tertiary care hospitals in Czech Republic, Slovak Republic, and Hungary. All submitted consecutive cases of cervical adenocarcinomas and cervical carcinomas with significant glandular component between 2003 and 2015 were reviewed in respective pathology departments and representative blocks/slides were sent for final evaluation based on the WHO 2014 classification by a panel of 2 pathologists with special interest in cervical pathology.