Abstract
Menopause hormone therapy is the best therapy for acute climacteric syndrome, osteoporosis' prevention and urogenital atrophy. It is absolutely safety in personal history of cervical cancer, endometrial cancer, hematologic malignancies, local malignant melanoma, colorectal cancer and liver cancer.
It is strictly contraindicated in cases history of breast cancer, endometrial stromal sarcoma, meningioma and estrogen receptor positive gastric and bladder cancer.