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Complete Nucleotide Sequences of mcr-4.3-Carrying Plasmids in Acinetobacter baumannii Sequence Type 345 of Human and Food Origin from the Czech Republic, the First Case in Europe

Publication at Faculty of Medicine in Pilsen, Faculty of Medicine in Hradec Králové |
2019

Abstract

Here we describe two plasmids carrying mcr-4.3 in two Acinetobacter baumannii strains isolated from imported food and a clinical sample. The comparative analysis of these plasmids, with two other plasmids reported in NCBI database, highlighted the common origin of the plasmidic structure carrying mcr-4.3.

This is the first case of mcr-4.3 gene in A. baumannii strain isolated from a clinical case in Europe. We hypothesize that food import is initiating the spread in Czech Republic.