Leiomyosarcoma of the Larynx - Diagnosis and Treatment Protocol: A Case Report and Review of the Literature
Abstract
Leiomyosarcoma of the larynx is known as a very rare malignancy. Soft tissue sarcomas of the head and neck region account for 4-15% of all the soft tissue sarcomas and less than 1% of all the neoplasms in this region.
The leiomyosarcomas in this area originate from blood vessels or smooth muscles. Some authors described the development of a leiomyosarcoma from the heterotopic mesenchymal tissue in the larynx.
The histological diagnosis of the leiomyosarcoma depends on the histology and the immunohistochemical investigation. The case presented here is of a 35-year-old man suffering of shortness of breath and hoarseness.
Indirect laryngoscopy showed a pedunculated tumor on the right vocal cord and petiolus epiglotis lesion causing no airway obstruction in the first time with rapid growing of them in the short time during the initial chemotherapy caused the suffocation. The case presented is one of a laryngeal leiomysoarcoma with the clinical, radiological and histological findings and therapy results.
We are presenting a new case of primary leiomyosarcoma of the larynx.