Publication at Faculty of Medicine in Hradec Králové |
2019
Abstract
We report a case of a 38-year-old woman with metastatic melanoma who developed unusual nivolumab-induced hepatic injury after a single dose of nivolumab. A liver biopsy was performed to assess the aetiology of hepatic lesions as no other analysis concerning biochemistry, virology, autoantibodies, nor imaging studies revealed any pathology.
To our knowledge, no such histopathological pattern of liver injury has been described in relation to nivolumab therapy elsewhere.