Refractory myasthenia gravis - clinical characteristics and possibilities of biological treatment

Abstract

Refractory myasthenia gravis, despite significant advances in the diagnosis and therapy of this autoimmune disease, is an important medical and socioeconomic problem. The article deals with the immunopathogenesis of myasthenia gravis, the characteristics of the disease, the clinical context in terms of risk groups of patients, the quantification of neurological deficits and the treatment options aimed at biological therapy.

Keywords

• myasthenia gravis
• MuSK
• refractory form
• clinical characteristics
• biological therapy