Publication at Faculty of Medicine in Hradec Králové |
2018
Abstract
Staphylococcus aureus is a human pathogen that causes infections of the skin and soft tissues. It is responsible, e.g. for endocarditis, pneumonia, or toxic shock syndrome.
It is also a common cause of bacteremia. Approximately 30% of the world's human population is colonized asymptomatically.
Diseases caused by resistant strains (MRSA, methicillin-resistant S. aureus) in association with an ineffective antibiotic therapy are responsible for an increased mortality. Therefore, the development of S. aureus vaccine is an important issue and the results of research in this area of general importance.