Testing algorithm for identification of patients with NTRK gene fusions in malignancies in the era of precision medicine and targete therapy with larotrectinib

Abstract

Detection of NTRK gene fusions offers a precision medicine approach to the patients using targeted therapy with selective TRK-inhibitors, such as larotrectinib.

Keywords

• precision medicine
• NTRK gene fusions
• targeted therapy
• tyrosine kinase-inhibitors