Abstract
The 2TVL SET system of extracorporeal circuit is designed for tempering (heating and cooling) of blood in extracorporeal circuits in preclinical experiments with large animals. Blood from the optional blood vessels of the experimental animal is drawn in by a controlled intake and then passes through the secondary part of the heat exchanger, where the blood is tempered (cooled).
It then passes through the head of a circulating pump, which pumps the blood to the secondary circuit of the second exchanger, where the blood is tempered (heated) to a temperature corresponding to the physiological temperature of the experimental animal and returned to the animal by connection to an optional vessel. The system consists of a sterile set (own extracorporeal circuit design) consisting of PVC hoses (biocompatible PVC and silicone), connecting and regulating components (biocompatible PS) and two heat exchangers with laminarizer of our construction.
Pumping of blood (or other solutions) through the extracorporeal circuit is provided by a contactless centrifugal blood pump with speed control and flow measurement. The set includes ports, allowing connection of sensors for temperature and pressure measurement.
The heat exchanger is tempered by the primary circuit, which is connected to the circulation source of the tempering liquid. For controlling, monitoring and recording the physical quantities in the circuit (measuring pressure and temperature at key locations, temperature control and flow of quench liquid through the primary circuit pump) is used biomonitor of our design (HW and SW).