Prevention and treatment of osteoporosis: causal or symptomatic? Prevence a léčba osteoartrózy: kauzální, nebo symptomatická? Prevention and treatment of osteoporosis: causal or symptomatic?
Abstract
Theseverity of the health and socio-economicconsequences of osteoporosis in women and in men increases with increasing life expectancy and the ageing of the population. The potential to reduce these risks is with causal mea- sures.
Syndrome of osteoporosis represents clinical manifestation of aging (involutional osteoporosis) and chronic diseases (secondary osteoporosis). In subjects with involutional bone loss, the physical activity and low inflamma- tory index diet appears an effective causal measure in the prevention of osteoporosis and fractures, In secondary osteoporosis, an effective first-line option is treatment of the underlying disease; during early postmenopause hor- monal therapy or selective estrogen receptor modulators should be considered.
Otherwise, in people with signifi- cantly high fracture risk, symptomatic antiresorptive or bone anabolic therapy is available.